Article

Transcriptomic changes resulting from <i>STK32B</i> overexpression identifies pathways potentially relevant to essential tremor

2019-02-18

Abstract excerpt

Essential tremor (ET) is a common movement disorder that has a high heritability. A number of genetic studies have associated different genes and loci with ET, but few have investigated the biology of any of these genes. STK32B was significantly associated with ET in a large GWAS study and was found to be overexpressed in ET cerebellar tissue. Here, we overexpressed STK32B in human cerebellar DAOY cells and used...

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Literature Corpus work: 7572f344-8a7a-5805-9ef2-8a9a3432a5a4
DOI: 10.1101/552901

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