Article

Adaptive Clonal Expansion Shapes Brain Development

2025-03-04

Abstract excerpt

Embryonic neural stem/progenitor cells (NSPCs) exhibit remarkable proliferative plasticity, allowing them to fully recover neuronal populations even after substantial cell loss 1,2 . However, it remains unclear whether all embryonic NSPCs respond to brain lesions. To address this, we developed a mouse model to investigate NSPC proliferation dynamics, hypothesizing that the loss of progenitor cells would induce fi...

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Literature Corpus work: 754b024c-c1c7-51c1-8cc4-5a287750e5ec
DOI: 10.1101/2025.03.04.641452

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