Article

Optimal Timing of Prophylactic Anticoagulation in Traumatic Brain Injury: A Target Trial Emulation

2025-11-20

Abstract excerpt

<title>Abstract</title> <p>Purpose To estimate the mortality‑minimizing time to initiate pharmacologic venous thromboembolism (VTE) prophylaxis after traumatic brain injury (TBI) in ICU patients and to identify patient phenotypes that may benefit from earlier vs later initiation. Methods We emulated a target trial in the National Trauma Data Bank (2019–2021) using a 24‑hour landmark and clone–censor–weight approa...

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Literature Corpus work: 7529d15d-d12f-50c4-aff1-90410b360d50
DOI: 10.21203/rs.3.rs-7904113/v1

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