Article

Additional Evidence Implicating GPD1L in the Pathogenesis of Brugada Syndrome in A Large Multi-generational Family

2022-09-20

Abstract excerpt

<h4>Background</h4> Brugada Syndrome (BrS) is an inherited arrhythmia syndrome in which mutations in SCN5A account for 20% of cases. Mutations in other ion channels or channel-modifying genes may account for an additional 10% of cases, though recent analysis has suggested that SCN5A should be regarded as the sole monogenic cause of BrS. <h4>Objective</h4> We sought to re-assess the genetic underpinnings of BrS in...

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Literature Corpus work: 74f32c84-93f7-5529-9fe2-466fe026cb53
DOI: 10.1101/2022.09.17.22280058

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