Article
The genetic basis of Brugada syndrome: a mutation update.
Human mutation - 1 Sept 2009
Hedley Paula L, Jørgensen Poul, Schlamowitz Sarah, Moolman-Smook Johanna, Kanters Jørgen K, Corfield Valerie A, Christiansen Michael
Abstract excerpt
Brugada syndrome (BrS) is a condition characterized by a distinct ST-segment elevation in the right precordial leads of the electrocardiogram and, clinically, by an increased risk of cardiac arrhythmia and sudden death. The condition predominantly exhibits an autosomal dominant pattern of inheritance with an average prevalence of 5:10,000 worldwide. Currently, more than 100 mutations in seven genes have been...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.