Article
The genetic basis of Brugada syndrome: a mutation update.
Human mutation - 1 Sept 2009
Hedley Paula L, Jørgensen Poul, Schlamowitz Sarah, Moolman-Smook Johanna, Kanters Jørgen K, Corfield Valerie A, Christiansen Michael
Abstract excerpt
Brugada syndrome (BrS) is a condition characterized by a distinct ST-segment elevation in the right precordial leads of the electrocardiogram and, clinically, by an increased risk of cardiac arrhythmia and sudden death. The condition predominantly exhibits an autosomal dominant pattern of inherit...
Topics
- Brugada Syndrome
- Calcium Channels, L-Type
- Humans
- Mutation
- NAV1.3 Voltage-Gated Sodium Channel
- Potassium Channels
- Potassium Channels, Voltage-Gated
- Sodium Channels
- Voltage-Gated Sodium Channel beta-1 Subunit
- Voltage-Gated Sodium Channel beta-3 Subunit