Article
Resveratrol Blocks Retrotransposition of LINE-1 Through PPAR α and Sirtuin-6
2021-09-14
Abstract excerpt
The retroelement long interspersed element-1 ( LINE-1 or L1) comprises about 17% of the human genome. L1 retrotransposition is known to cause genomic instability and related disorders, and resveratrol suppresses this retrotransposition; however, the underlying mechanism is still not elucidated. Recent observations showed that low-molecular-weight compounds might induce L1 retrotransposition through unknown mechani...
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Identifiers and source
- Literature Corpus work
- 74a8e50c-c753-5560-9675-fd0d12dcef22
- DOI
- 10.21203/rs.3.rs-860434/v1
