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An Enhanced Split Intein-Mediated Ligation (SIML) Platform for Rapid Discovery and Functional Screening of Circular Bacteriocins

2026-05-22

Abstract excerpt

Bacteriocins are ribosomally synthesized antimicrobial peptides with promising applications in biotechnology, particularly in food preservation and animal and human health. Circular bacteriocins are especially attractive due to their head-to-tail cyclized structure, which confers enhanced stability and antimicrobial potency relative to linear peptides. Here, we report an in vitro cell-free protein synthesis syste...

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Literature Corpus work
74800ab4-206c-51ae-92b2-0234827099dc
DOI
10.64898/2026.05.21.726877
Open publication

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An Enhanced Split Intein-Mediated Ligation (SIML) Platform for Rapid Discovery and Functional Screening of Circular BacteriocinsDOI 10.64898/2026.05.21.726877
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