Article

Unsupervised Clustering Reveals Spatially Varying Single Neuronal Firing Patterns in the Subthalamic Nucleus of Patients with Parkinson’s Disease

2019-12-08

Abstract excerpt

<h4>Introduction</h4> Subthalamic nucleus (STN) is an effective target for deep brain stimulation (DBS) to reduce the motor symptoms of Parkinson’s disease (PD). It is important to identify firing patterns within the structure for a better understanding of the electro-pathophysiology of the disease. Using recently established metrics, our study aims to autonomously identify the discharge patterns of individual ce...

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Literature Corpus work: 74551a1f-41d3-5de4-99ad-4c15c6dbd35f
DOI: 10.1101/863464

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