Article
RBCeq: A robust and scalable algorithm for accurate genetic blood typing.
EBioMedicine - 1 Feb 2022
Jadhao Sudhir, Davison Candice L, Roulis Eileen V, Schoeman Elizna M, Divate Mayur, Haring Mitchel, Williams Chris, Shankar Arvind Jaya, Lee Simon, Pecheniuk Natalie M, Irving David O, Hyland Catherine A, Flower Robert L, Nagaraj Shivashankar H
Abstract excerpt
BACKGROUND: While blood transfusion is an essential cornerstone of hematological care, patients requiring repetitive transfusion remain at persistent risk of alloimmunization due to the diversity of human blood group polymorphisms. Despite the promise, user friendly methods to accurately identify blood types from next-generation sequencing data are currently lacking. To address this unmet need, we have developed...
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