Article
High-throughput targeted amplicon screening tool for characterizing intrahost diversity in Staphylococcus aureus directly from sample.
Microbial genomics - 1 Jun 2025
Furstenau Tara N, Whealy Ryann, Timm Skylar, Roberts Alexander, Maltinsky Sara, Wells Sydney J, Drake Kylie, Ross Ann, Bolduc Candice, Pearson Talima, Fofanov Viacheslav Y
Abstract excerpt
A significant proportion of people are asymptomatic carriers of Staphylococcus aureus (SA), an important risk factor for the development of opportunistic infections. SA colonization is dynamic, appearing and disappearing, with strains evolving and potentially shifting in composition over time and between body sites. These changes make detection challenging, and the numerous potential sources of reintroduction...
Topics
- Humans
- Staphylococcus aureus
- Staphylococcal Infections
- Carrier State
- High-Throughput Nucleotide Sequencing
- Whole Genome Sequencing
- Genotype
- Mouth
- High-Throughput Screening Assays