Article
Ligand-dependent Wnt signaling promotes gastric cancer metastasis through hyaluronan expression in microenvironment
2025-03-04
Abstract excerpt
<title>Abstract</title> <p> The majority of gastric cancer cells proliferate in a Wnt ligand-dependent manner. In this study, we examined the role of ligand-dependent Wnt signaling in the development and metastasis of gastric cancer. We generated mice with mutations in <italic>Kras</italic> , <italic>Tgfbr2</italic> , and <italic>Trp53</italic> (KTP mice) as well as mice with the same mutations plus <ital...
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Identifiers and source
- Literature Corpus work
- 73f172d6-493c-5f2a-8a1b-0a96b7e98703
- DOI
- 10.21203/rs.3.rs-6018512/v1