Article
Laminin gamma2 mediates Wnt5a-induced invasion of gastric cancer cells.
Gastroenterology - 1 Jul 2009
Yamamoto Hideki, Kitadai Yasuhiko, Yamamoto Hideki, Oue Naohide, Ohdan Hideki, Yasui Wataru, Kikuchi Akira
Abstract excerpt
BACKGROUND & AIMS: Wnt5a expression stimulates in vitro migration and invasion of cultured gastric cancer cells by an unknown mechanism and is also correlated with aggressiveness of gastric tumors. The aim of this study was to show that Wnt5a is involved in metastasis of gastric cancer cells in vivo and to explore the molecular mechanism by which Wnt5a regulates migration and invasion. METHODS: In an experimental...
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