Article

A Novel Frameshift Mutation in F9 in a Mixed Breed Dog With Clinical Hemophilia B

2020-08-19

Abstract excerpt

<title>Abstract</title> <p>A male mixed breed dog with clinical Hemophilia B was tested with a direct-to-consumer dog genomics service. After being genotyped as “normal” at three previously published Hemophilia B variants, all coding regions of the dog’s F9 gene were sequenced. A single basepair deletion in exon 5 of F9 led to a frameshift mutation leading to a premature truncation of FIX, including loss of the c...

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Literature Corpus work: 73a612ba-9dbf-5736-9a95-fd676f70d49d
DOI: 10.21203/rs.3.rs-59504/v1

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