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Article

A Single Base Insertion in F9 Causing Hemophilia B in a Family of Newfoundland-Parti Standard Poodle Hybrid Dogs.

Genes - 24 Sept 2021

Kuder Henrike, Sandzhieva-Vuzzo Liubov, Kehl Alexandra, Rappaport Jonathan M, Müller Elisabeth, Giger Urs

Abstract excerpt

Hemophilia B is an x-linked recessive hereditary coagulopathy that has been reported in various species. We describe a male Newfoundland-Parti Standard Poodle hybrid puppy and its family with hemophilia B from clinical manifestations to the molecular genetic defect. The index case presented for dyspnea was found to have a mediastinal hematoma, while surgical removal and transfusion support brought some relief,...

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Identifiers

PMID: 34680886
DOI: 10.3390/genes12101491
PMCID: PMC8535623

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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