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Article

A Line 1 insertion in the Factor IX gene segregates with mild hemophilia B in dogs.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 2003

Brooks Marjory B, Gu Weikuan, Barnas Jennifer L, Ray Jharna, Ray Kunal

Abstract excerpt

We undertook the biochemical and molecular characterization of hemophilia in a large pedigree of German wirehaired pointers. Males affected with hemophilia B had approximately 5% normal Factor IX coagulant activity and a proportional reduction of Factor IX protein concentration, indicative of a m...

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PMID: 14722728
DOI: 10.1007/s00335-003-2290-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14722728-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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