Article

ACE 2 Coding Variants: A Potential X-linked Risk Factor for COVID-19 Disease

2020-04-14

Abstract excerpt

Viral genetic variants are widely known to influence disease progression among infected humans. Given the recent and rapid emergence of pandemic SARS-CoV-2 infection, the cause of COVID-19 disease, viral protein variants have attracted research interest. However, little has yet been written about genetic risk factors among human hosts. Human genetic variation has proven to affect disease progression and outcome fo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7387d9ba-b94b-5b06-99d0-af9b19641aa3
DOI: 10.1101/2020.04.05.026633

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ACE 2 Coding Variants: A Potential X-linked Risk Factor for COVID-19 DiseaseDOI 10.1101/2020.04.05.026633Read

SARS-CoV-2 Susceptibility and ACE2 Gene Variations Within Diverse Ethnic BackgroundsSemantic proximity Read

SARS-CoV-2 susceptibility and <i>ACE2</i> gene variations within diverse ethnic backgroundsSemantic proximity Read

COVID-19 genomic susceptibility: Definition of <i>ACE2</i> variants relevant to human infection with SARS-CoV-2 in the context of ACMG/AMP GuidanceSemantic proximity Read

Assessing COVID-19 Susceptibility Through Analysis of the Genetic and Epigenetic Diversity of ACE2-Mediated SARS-CoV-2 EntrySemantic proximity Read

Genome-wide analysis in 756,646 individuals provides first genetic evidence that <i>ACE2</i> expression influences COVID-19 risk and yields genetic risk scores predictive of severe diseaseSemantic proximity Read

Lineage-specific positive selection on ACE2 contributes to the genetic susceptibility of COVID-19Semantic proximity Read

Effects of selected inherited factors on susceptibility to SARS-CoV-2 infection and COVID-19 progression.Semantic proximity Read

Are COVID-19 Polymorphisms in ACE and ACE2 Prognosis Predictors?Semantic proximity Read

ACE2 polymorphisms as potential players in COVID-19 outcomeSemantic proximity Read

New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysisSemantic proximity Read

Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe diseaseSemantic proximity Read

ACE2 polymorphisms as potential players in COVID-19 outcome.Semantic proximity Read