Article

Model integration of circadian and sleep-wake driven contributions to rhythmic gene expression reveals novel regulatory principles

2023-08-14

Abstract excerpt

Transcriptome studies aim at gaining insight into the molecular pathways underlying biological processes. Analyses of gene-expression dynamics in research on circadian rhythms and sleep homeostasis describe these two processes independently, using separate models such as sinusoidal oscillations and exponential saturating functions. Rhythmically expressed genes are, however, influenced by both processes. We therefo...

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Literature Corpus work: 735f7771-4fe8-5169-8d7c-eb0e7a931bd9
DOI: 10.1101/2023.08.10.552614

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