Article
Circadian clock genes and sleep homeostasis.
The European journal of neuroscience - 1 May 2009
Franken P, Dijk D-J
Abstract excerpt
Circadian and sleep-homeostatic processes both contribute to sleep timing and sleep structure. Elimination of circadian rhythms through lesions of the suprachiasmatic nuclei (SCN), the master circadian pacemaker, leads to fragmentation of wakefulness and sleep but does not eliminate the homeostatic response to sleep loss as indexed by the increase in EEG delta power. In humans, EEG delta power declines during...
Topics
- Animals
- Brain
- Cell Cycle Proteins
- Circadian Rhythm
- Gene Expression
- Homeostasis
- Humans
- Intracellular Signaling Peptides and Proteins
- Mice
- Nuclear Proteins
- Period Circadian Proteins
- Phenotype