Article

Circulating HIF-1α and VEGF as Potential Biomarkers in Connective Tissue Disease-associated Pulmonary Arterial Hypertension

2024-10-15

Abstract excerpt

<title>Abstract</title> <p><bold>Objective:</bold>Pulmonary arterial hypertension (PAH) is an independent risk factor for increased mortality in patients with connective tissue disease (CTD); however, early diagnosis remains challenging. We aimed to assess the serum levels of hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) and explore their clinical significance in patients with...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 72df9d31-4bde-525e-9cb3-9caa572426bc
DOI: 10.21203/rs.3.rs-4895122/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Circulating HIF-1α and VEGF as Potential Biomarkers in Connective Tissue Disease-associated Pulmonary Arterial HypertensionDOI 10.21203/rs.3.rs-4895122/v1Read

Diversity of hemodynamic types in connective tissue disease associated pulmonary hypertension: more than a subgroup of pulmonary arterial hypertensionSemantic proximity Read

Hypoxia Inducible Factor-1α in Pulmonary Fibrosis: A Promising Therapeutic TargetSemantic proximity Read

Hypoxia-Inducible Factor 1α Is a Critical Downstream Mediator for Hypoxia-Induced Mitogenic Factor (FIZZ1/RELMα)-Induced Pulmonary Hypertension.Semantic proximity Read

Hypoxia modulates human pulmonary arterial adventitial fibroblast phenotype through HIF-1α activationSemantic proximity Read

Pulmonary arterial hypertension in connective tissue diseases.Semantic proximity Read

New phenotype and outcomes in connective tissue disease-associated pulmonary arterial hypertension: relevance of age-related comorbidities.Semantic proximity Read

Recent Advances in the Treatment of Pulmonary Arterial Hypertension Associated with Connective Tissue DiseasesSemantic proximity Read

Prognosis and response to first-line single and combination therapy in pulmonary arterial hypertension.Semantic proximity Read

The association of genetic polymorphisms of hypoxia inducible factor-1 alpha and vascular endothelial growth factor with increased risk of chronic obstructive pulmonary disease: A case-control study.Semantic proximity Read

Functional Repercussions of Hypoxia-Inducible Factor-2α in Idiopathic Pulmonary FibrosisSemantic proximity Read

Imbalance of fetal growth factor levels in congenital heart disease pathology: a systematic review to investigate therapeutic potentialSemantic proximity Read

Elevated HIF-1α as a diagnostic biomarker in COPD: Correlations with EPO, emphysema index, and pulmonary function.Semantic proximity Read