Article

Single-cell landscape of bone marrow metastases in human neuroblastoma unraveled by deep multiplex imaging

2020-09-30

Abstract excerpt

<h4>ABSTRACT</h4> Bone marrow commonly serves as a metastatic niche for disseminated tumor cells (DTCs) of solid cancers in patients with unfavorable clinical outcome. Single-cell assessment of bone marrow metastases is essential to decipher the entire spectrum of tumor heterogeneity in these cancers, however, has previously not been performed. Here we used multi-epitope-ligand cartography (MELC) to spatially pro...

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Literature Corpus work: 72bc6464-41be-591a-b2ad-b072d362b435
DOI: 10.1101/2020.09.30.321539

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