Article
A Chimeric Oncolytic Adenovirus Carried by Macrophages for Glioma Immunotherapy
2025-04-01
Abstract excerpt
<title>Abstract</title> <p>Purpose: Oncolytic viruses hold promise as a novel frontier in glioma immunotherapy; however, current oncolytic viruses often face challenges of inadequate glioma infiltration and limited viral persistence in clinical settings. Macrophages, with their ability to effectively infiltrate glioma tissue, have emerged as potential cell vectors; however, they naturally resist virus infection....
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Identifiers and source
- Literature Corpus work
- 725dd2d6-756f-56c9-b1e5-de0d42d72fcb
- DOI
- 10.21203/rs.3.rs-6291711/v1