Article

Valproic acid stimulates myogenesis in pluripotent stem cell–derived mesodermal progenitors in a Notch-dependent manner

2020-12-16

Abstract excerpt

<h4>ABSTRACT</h4> Muscular dystrophies are debilitating neuromuscular disorders for which no cure exists. As this disorder affects both cardiac and skeletal muscle, patients would benefit from a cellular therapy that can simultaneously regenerate both tissues. The current protocol to derive bipotent mesodermal progenitors which can differentiate into cardiac and skeletal muscle relies on the spontaneous formation...

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Literature Corpus work: 725459f9-1c69-5ece-9318-d149f112f936
DOI: 10.1101/2020.12.16.423053

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