Article
Activating Transcription Factor 5 (ATF5) Promotes Tumorigenic Capability and Activates the Wnt/b-Catenin Pathway in Bladder Cancer
2021-09-16
Abstract excerpt
<title>Abstract</title> <p>Background In bladder cancer, up to 70% of patients will relapse after resection within 5 years, in which the mechanism underlying the recurrence remains largely unclear. Methods Quantitative real-time PCR, western blot and immunohistochemistry were conducted. The assays of tumor sphere formation and tumor xenograft were further performed to assess the potential biological roles of AT...
Topics
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- Bladder and Urothelial Cancer Treatments
- Cancer, Hypoxia, and Metabolism
- Cancer-related molecular mechanisms research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Epigenetics and DNA Methylation
- Genomics, phytochemicals, and oxidative stress
- RNA modifications and cancer
- Wnt/β-catenin signaling in development and cancer
Identifiers and source
- Literature Corpus work
- 723383d6-ea3e-5e38-832f-8f2840a16f11
- DOI
- 10.21203/rs.3.rs-882687/v1