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Article

Risk Variants in the Exomes of Children With Critical Illness

28 Oct 2022

Abstract excerpt

Importance: Diagnostic genetic testing can lead to changes in management in the pediatric intensive care unit. Genetic risk in children with critical illness but nondiagnostic exome sequencing (ES) has not been explored. Objective: To assess the association between loss-of-function (LOF) variants and pediatric critical illness. Design, Setting, and Participants: This genetic association study examined ES first...

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PMID: 36306130
DOI: 10.1001/jamanetworkopen.2022.39122

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