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Article

Rational design of competitive prolactin/growth hormone receptor antagonists.

Journal of mammary gland biology and neoplasia - 1 Mar 2008

Tallet Estelle, Rouet Vincent, Jomain Jean-Baptiste, Kelly Paul A, Bernichtein Sophie, Goffin Vincent

Abstract excerpt

There is increasing evidence that prolactin (PRL) and growth hormone (GH) act as growth-promoters of breast tumors. Recent arguments have accumulated to suggest that when they are locally-produced within the mammary tissue, these hormones, acting by an autocrine-paracrine mechanism may have enhanced, or even specific functions compared to endocrine PRL and GH. Classical drugs blocking pituitary hormone production...

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Source

Identifiers

PMID: 18219565
DOI: 10.1007/s10911-008-9066-8

Genes

PRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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