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Identification of Tumor Mutation Burden, Microsatellite Instability, and Somatic Copy Number Alteration derived 9-gene Signatures to Predict Clinical Outcomes in STAD

2021-10-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Genomic features including tumor mutation burden (TMB), microsatellite instability (MSI) and somatic copy number alteration (SCNA), had been demonstrated to be involved with the tumor microenvironment (TME) and outcome of gastric cancer (GC). <bold>Methods: </bold>We obtained profiles of TMB, MSI and SCNA by processing 405 GC data from The Cancer Genome Atlas (T...

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Literature Corpus work: 71fb3a6f-e704-5e6f-a25d-68c545bc2ea3
DOI: 10.21203/rs.3.rs-956254/v1

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