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Multi omics reveals mesodermal fate bias and enables predictive cell state control in human pluripotent stem cell biomanufacturing

2026-05-29

Abstract excerpt

Despite accelerating interest in using human induced pluripotent stem cell (hiPSC)–derived products for disease modeling and therapeutic development, there is substantial evidence that conventional culture approaches do not fully recapitulate natural embryonic nor lineage-committed states. It remains poorly understood how in vitro environmental conditions cause divergence from natural developmental trajectories,...

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Literature Corpus work
71ebd46b-9f68-523c-9bc2-573b401fbdf8
DOI
10.64898/2026.05.26.727850
Open publication

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Multi omics reveals mesodermal fate bias and enables predictive cell state control in human pluripotent stem cell biomanufacturingDOI 10.64898/2026.05.26.727850
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