Article

Molecular Programs of Glomerular Hyperfiltration in Early Diabetic Kidney Disease

2021-09-16

Abstract excerpt

Hyperfiltration (HF) is a state of high glomerular filtration rate (GFR) observed in early diabetes that damages glomeruli, resulting in an iterative process of increasing filtration load on fewer and fewer remaining functional glomeruli. To delineate underlying cellular mechanisms of damage induced by HF, transcriptional profiles of kidney biopsies from Pima Indians with type 2 diabetes with or without early-stag...

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Literature Corpus work: 71d87669-555a-56b4-a24f-d42cc30b951e
DOI: 10.1101/2021.09.13.21263340

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