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Article

A molecular morphometric approach to diabetic kidney disease can link structure to function and outcome.

Kidney international - 1 Feb 2018

Nair Viji, Komorowsky Claudiu V, Weil E Jennifer, Yee Berne, Hodgin Jeffrey, Harder Jennifer L, Godfrey Bradley, Ju Wenjun, Boustany-Kari Carine M, Schwarz Margrit, Lemley Kevin V, Nelson Peter J, Nelson Robert G, Kretzler Matthias

Abstract excerpt

Diabetic kidney disease is the leading cause of kidney failure. However, studies of molecular mechanisms of early kidney damage are lacking. Here we examined for possible linkage between transcriptional regulation and quantitative structural damage in early diabetic kidney disease in Pima Indians with type 2 diabetes. Tissue obtained from protocol kidney biopsies underwent genome-wide compartment-specific gene...

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Identifiers

PMID: 29054530
DOI: 10.1016/j.kint.2017.08.013
PMCID: PMC5794609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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