Article

IFN-beta promotes RSAD2 expression and Lupus plasma cell differentiation via DNA Demethylation

2024-04-02

Abstract excerpt

<h4>Background: </h4> Systemic lupus erythematosus (SLE) is an autoimmune disease, in which the pathogenesis is revealed as abnormalities in B cells with no clear mechanism. Radical s-adenosyl methionine domain-containing 2 (RSAD2) is an interferon-stimulated gene (ISG), and it has been found to play an important role in innate immunity. Recent years the function of RSAD2 in autoimmune diseases, but its still unkn...

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Literature Corpus work: 71a70e13-f91e-5b2a-b4a2-129c1ea3aa22
DOI: 10.21203/rs.3.rs-4003534/v1

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