Article

A tRNA-acetylating toxin and detoxifying enzyme in <i>Mycobacterium tuberculosis</i>

2021-12-20

Abstract excerpt

Toxin-antitoxin (TA) systems allow bacteria to adapt to changing environments without altering gene expression. Despite being overrepresented in Mycobacterium tuberculosis ( Mtb ), their individual physiological roles remain elusive. We describe a TA system in Mtb which we have named TacAT due to its homology to previously discovered systems in Salmonella. The toxin, TacT, blocks growth by acetylating glycyl-tR...

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Identifiers and source

Literature Corpus work: 7151a7fb-8f02-593a-a6d6-65cf55a2727c
DOI: 10.1101/2021.12.20.473312

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