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Advances in Mammalian Cell Line Development Technologies for Recombinant Protein Production

26 Apr 2013

Abstract excerpt

From 2006 to 2011, an average of 15 novel recombinant protein therapeutics have been approved by US Food and Drug Administration (FDA) annually. In addition, the expiration of blockbuster biologics has also spurred the emergence of biosimilars. The increasing numbers of innovator biologic products and biosimilars have thus fuelled the demand of production cell lines with high productivity. Currently, mammalian...

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PMID: 24276168
DOI: 10.3390/ph6050579

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