Article

Dual IgA/IgG family autoantibodies from individuals at-risk for rheumatoid arthritis identify an arthritogenic strain of <i>Subdoligranulum</i>

2022-06-12

Abstract excerpt

The mucosal origins hypothesis of rheumatoid arthritis (RA) proposes a central role for mucosal immune responses in the initiation and/or perpetuation of the systemic autoimmunity that occurs with disease. However, the connection between the mucosa and systemic autoimmunity in RA remains unclear. Using dual IgA/IgG family plasmablast-derived monoclonal autoantibodies obtained from peripheral blood of individuals a...

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Literature Corpus work: 709b526a-fb15-5e3f-ab42-1cf22ace0788
DOI: 10.1101/2022.06.09.495381

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