Article

Functional characterization of the human PRUNE protein : implications in cancer

2004-01-01

Abstract excerpt

The functional characterization of <i>H-PRUNE</i> was performed using different approaches, in order to elucidate first the biochemical function of the protein, and then the correlation with other genes and the role in different tumour types. First, we identified and characterized H-PRUNE phosphodiesterase activity, which is suppressed by dipyridamole. Interestingly, H-PRUNE interacts with NM23-Hl, an anti-metasta...

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Literature Corpus work: 7078c017-ec6e-57cd-99c6-a115f02feeb4
DOI: 10.21954/ou.ro.0000fa04

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