Article

Metabolomics pilot study identifies circadian desynchronization and distinct intra-patient variability patterns in critical illness

2019-12-14

Abstract excerpt

<h4>Background</h4> Synchronized circadian rhythms play a key role in coordinating physiologic health. Desynchronized circadian rhythms may predispose individuals to disease or be indicative of underlying disease. Intensive care unit (ICU) patients likely experience desynchronized circadian rhythms due to disruptive environmental conditions in the ICU and underlying pathophysiology. This observational pilot study...

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Literature Corpus work: 7075e665-f80d-57cd-a043-756b17e367b4
DOI: 10.1101/2019.12.09.19014225

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