Article

The Role of Sodium Phenylbutyrate and Suramin in the Prevention of Ulcerative Colitis Induced by Dextran Sulfate Sodium

2024-04-09

Abstract excerpt

<title>Abstract</title> <p>Ulcerative colitis is an inflammatory bowel disease characterized by inflammation and increased oxidative stress in the colon tissue. Sodium phenylbutyrate (PBA) and suramin are histone deacetylase inhibitors that alter gene expression keeping histones in the acetylated form. Our aim in this study was to determine the effects of PBA and suramin on colon tissue in an acute colitis model...

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Literature Corpus work: 707388fb-a27f-55ff-9527-90747f4f883d
DOI: 10.21203/rs.3.rs-4211305/v1

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