Article

Insulinase like protease 1 contributes to macrogamont formation in <i>Cryptosporidium parvum</i>

2020-12-04

Abstract excerpt

The apicomplexan parasite Cryptosporidium parvum contains an expanded family of 22 insulinase like proteases (INS), a feature that contrasts with their otherwise streamlined genome. Here we examined the function of INS1, which is most similar to the human insulinase protease that cleaves a variety of small peptide substrates. INS1 is a M16A clan member and contains a signal peptide, an N-terminal domain with the...

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Literature Corpus work: cff077fd-3e9c-5043-83af-705afee2234c
DOI: 10.1101/2020.12.03.411165

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