HCS-3D <i>X</i> , a next-generation AI-driven automated 3D-oid high-content screening system

Abstract excerpt

Self-organized three-dimensional (3D) cell cultures, collectively called 3D-oids, include spheroids, organoids and other co-culture models. Systematic evaluation of these models forms a critical new generation of high-content screening (HCS) systems for patient-specific drug analysis and cancer research. However, the standardisation of working with 3D-oids remains challenging and lacks convincing implementation. T...

Topics

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• Cell Culture Techniques
• Cell Image Analysis Techniques
• Cell Survival
• Drug Evaluation, Preclinical
• High-Throughput Screening Assays
• Mice
• Organoids
• Phenotype

Identifiers and source

Literature Corpus work

70230b70-3b16-5a59-8b05-33f8c33cd18b

DOI

10.1101/2024.07.15.603536