Article

Molecular Investigation of TSHR gene in Bangladeshi Congenital Hypothyroid patients

2023-02-21

Abstract excerpt

The disorder of thyroid gland development or thyroid dysgenesis (TH) accounts for 80-85% cases of congenital hypothyroidism (CH). Hence, the understanding of molecular etiology of TH is prerequisite. Mutations in TSHR gene is mostly associated with thyroid dysgenesis, prevent or disrupt normal development of the gland. The current study detects two nonsynonymous mutations (p.Ser508Leu, p.Asp727Glu) in transmembran...

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Literature Corpus work: 6fdfea03-98c8-564e-be30-d6e62fd77f7a
DOI: 10.1101/2023.02.20.529210

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