Human papillomaviruses: diversity, infection and host interactions.

Abstract excerpt

Human papillomaviruses (HPVs) are an ancient and highly successful group of viruses that have co-evolved with their host to replicate in specific anatomical niches of the stratified epithelia. They replicate persistently in dividing cells, hijack key host cellular processes to manipulate the cellular environment and escape immune detection, and produce virions in terminally differentiated cells that are shed from...

Topics

• Alphapapillomavirus
• Evolution, Molecular
• Genetic Variation
• Host-Pathogen Interactions
• Humans
• Papillomavirus Infections