GPnotebook: A pan-cancer glycoproteomic database and toolkit for analysis of protein glycosylation changes associated with cancer phenotypes

Abstract excerpt

Protein glycosylation plays a pivotal role in various biological processes, and the analysis of intact glycopeptides (IGPs) has emerged as a powerful approach for characterizing alterations in protein glycosylation associated with diseases. Despite the critical insights gained from IGP analysis, there is an evident scarcity of intact glycopeptide database and specialized tools for a comprehensive glycoproteomic ex...

Topics

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• Galectins and Cancer Biology
• Glycosylation and Glycoproteins Research
• Immunotherapy and Immune Responses
• Lung Cancer Research Studies
• Monoclonal and Polyclonal Antibodies Research
• Neuroblastoma Research and Treatments
• Pancreatic and Hepatic Oncology Research
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

6fb967f4-ea77-5af6-b092-1582a6951fdc

DOI

10.1101/2024.04.18.589619