Article

Serotonin 2A Receptor Attenuates Psoriatic Inflammation by Suppressing IL-23 Secretion in Monocyte-derived Langerhans Cells

2025-01-06

Abstract excerpt

<title>Abstract</title> <p>Anecdotal evidence has suggested an association between psychiatric drugs and psoriasis but consensus is absent due to contradicting reports and the mechanism remains poorly defined. Here, we investigated the role played by serotonin 2A receptor (HTR2A), a receptor commonly targeted by psychiatric drugs, in regulating psoriasis. HTR2A antagonistic drugs worsened psoriatic outcome and HT...

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Literature Corpus work: 6fa11831-f3de-5ab4-acc9-0ee6a7402a70
DOI: 10.21203/rs.3.rs-5628384/v1

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