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Article

Genetic changes of non-small cell lung cancer under neoadjuvant therapy.

Oncotarget - 17 May 2016

Warth Arne, Endris Volker, Stenzinger Albrecht, Penzel Roland, Harms Alexander, Duell Thomas, Abdollahi Amir, Lindner Michael, Schirmacher Peter, Muley Thomas, Dienemann Hendrik, Fink Ludger, Morresi-Hauf Alicia, Pfarr Nicole, Weichert Wilko

Abstract excerpt

BACKGROUND: Large scale sequencing efforts defined common molecular alterations in non-small cell lung cancer (NSCLC) and revealed potentially druggable mutations. Yet, systematic data on the changes of the respective molecular profiles under standard therapy in NSCLC are limited. RESULTS: 14 out of 68 observed coding mutations (21%) and 6 out of 33 (18%) copy number variations (CNV) were lost or gained during...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27105513
DOI: 10.18632/oncotarget.8858
PMCID: PMC5045431

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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