Article

Involvement of the Extracellular Matrix Proteins Periostin and Tenascin C in Nasal Polyp Remodeling by Regulating the Expression of MMPs

2020-12-04

Abstract excerpt

<title>Abstract</title> <p>Background: Tissue remodeling caused by increased MMPs is involved in the pathogenesis of chronic rhinosinusitis with nasal polyposis (CRSwNP). We previously found higher levels of periostin and tenascin C in CRSwNPs, but whether they are associated with the dysregulation of MMPs is unknown. Therefore, the present study aimed to investigate the regulatory roles of two ECM proteins in th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6f5e0430-3313-5e69-93ba-5fc566e1a563
DOI: 10.21203/rs.3.rs-118180/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Involvement of the Extracellular Matrix Proteins Periostin and Tenascin C in Nasal Polyp Remodeling by Regulating the Expression of MMPsDOI 10.21203/rs.3.rs-118180/v1Read

Excessive periostin expression and Th2 response in patients with nasal polyps: association with asthmaSemantic proximity Read

Periostin as a Biomarker for Nasal Polyps in Chronic Rhinosinusitis.Semantic proximity Read

Overexpressed proprotein convertase 1/3 induces an epithelial-mesenchymal transition in airway epithelium.Semantic proximity Read

Nasal Polyposis: Insights in Epithelial-mesenchymal Transition and Differentiation of Polyp Mesenchymal Stem CellsSemantic proximity Read

The functional role and the clinical application of periostin in chronic rhinosinusitis.Semantic proximity Read

Polymorphisms in chronic rhinosinusitis with nasal polyps - a systematic review.Semantic proximity Read

NLRP3 participates in IL-17A-induced epithelial-mesenchymal transition in human nasal epithelial cells of chronic rhinosinusitis with nasal polypsSemantic proximity Read

Significance of CYCLOOXYGENASE-2(COX-2), PERIOSTIN (POSTN) and INTERLEUKIN-4(IL-4) gene expression in the pathogenesis of chronic rhinosinusitis with nasal polypsSemantic proximity Read

MicroRNAs regulating mucin type O‐glycan biosynthesis and transforming growth factor β signaling pathways in nasal mucosa of patients with chronic rhinosinusitis with nasal polyps in Northern ChinaSemantic proximity Read

Wound healing and fibrosis: a contrasting role for periostin in skin and the oral mucosa.Semantic proximity Read

Expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in recurrent chronic rhinosinusitis with nasal polyposis.Semantic proximity Read

Matrix metalloproteinase-9 gene polymorphisms in nasal polyposis.Semantic proximity Read