Article

NLRP3 participates in IL-17A-induced epithelial-mesenchymal transition in human nasal epithelial cells of chronic rhinosinusitis with nasal polyps

2024-07-19

Abstract excerpt

<title>Abstract</title> <p>Epithelial-mesenchymal transition (EMT) has been reported to occur in chronic rhinosinusitis with nasal polyps (CRSwNP). Various cytokines have been reported to promote EMT profiles. However, the relationship between IL-17A and EMT on human nasal epithelial cells (hNECs) have not been clarified. In this study, we detect the expression of IL-17A, NLRP3, TGF-β1, and EMT-related genes in n...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 94fff192-fb4e-5231-9895-85e3624511ec
DOI: 10.21203/rs.3.rs-4630578/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

NLRP3 participates in IL-17A-induced epithelial-mesenchymal transition in human nasal epithelial cells of chronic rhinosinusitis with nasal polypsDOI 10.21203/rs.3.rs-4630578/v1Read

Inhibition of IL-4/STAT6/IRF4 signaling reduces the epithelial-mesenchymal transition in eosinophilic chronic rhinosinusitis with nasal polypsSemantic proximity Read

Nasal Polyposis: Insights in Epithelial-mesenchymal Transition and Differentiation of Polyp Mesenchymal Stem CellsSemantic proximity Read

MicroRNAs regulating mucin type O‐glycan biosynthesis and transforming growth factor β signaling pathways in nasal mucosa of patients with chronic rhinosinusitis with nasal polyps in Northern ChinaSemantic proximity Read

Role of NLRP3 Inflammasome on Different Phenotypes of Chronic Rhinosinusitis.Semantic proximity Read

[Gene expression levels of cytokines in different phenotypes of CRSwNP].Semantic proximity Read

Excessive periostin expression and Th2 response in patients with nasal polyps: association with asthmaSemantic proximity Read

[Pleiomorphism of the cytokine profile in nasal polyp tissue depending on the phenotype of chronic rhinosinusitis with nasal polyps].Semantic proximity Read

Comparison of Gene Expression between Chronic Rhinosinusitis with Nasal Polyposis and without Nasal PolyposisSemantic proximity Read

Transcriptomics unravels molecular changes associated with cilia and COVID-19 in chronic rhinosinusitis with nasal polypsSemantic proximity Read

Features of mesenchymal transition in the airway epithelium from chronic rhinosinusitis.Semantic proximity Read

MBP-positive and CD11c-positive cells are associated with different phenotypes of Korean patients with non-asthmatic chronic rhinosinusitis.Semantic proximity Read

Identification and experimental validation of biomarkers associated with integrative stress response in chronic rhinosinusitis with nasal polypsSemantic proximity Read