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Article

Overexpressed proprotein convertase 1/3 induces an epithelial-mesenchymal transition in airway epithelium.

The European respiratory journal - 1 Nov 2013

Lee Sang-Nam, Lee Da-Hyung, Sohn Myung Hyun, Yoon Joo-Heon

Abstract excerpt

The proprotein convertases (PCs) are serine proteases responsible for the proteolytic maturation of many precursor proteins involved in upper airway remodelling during nasal polyposis. We have previously found that PC1/3 is expressed in human nasal mucosa. However, whether PC1/3 is related to nasal polyp formation has not been investigated. To gain insight into the functional role of PC1/3 in nasal polyps, we...

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Identifiers

PMID: 23314902
DOI: 10.1183/09031936.00100412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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