Article
Matrix metalloproteinase-9 gene polymorphisms in nasal polyposis.
BMC medical genetics - 9 Jun 2010
Wang Ling-Feng, Chien Chen-Yu, Tai Chih-Feng, Kuo Wen-Rei, Hsi Edward, Juo Suh-Hang Hank
Abstract excerpt
BACKGROUND: Matrix metalloproteinase (MMP) is involved in the upper airway remodeling process. We hypothesized that genetic variants of the MMP-9 gene are associated with cases of chronic rhinosinusitis with nasal polyposis. METHODS: We conducted a case-control study where 203 cases of chronic rhinosinusitis with nasal polyposis and 730 controls were enrolled. Three tagging single nucleotide polymorphisms (SNPs)...
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