Article

Denoising autoencoder-based bulk and single-cell RNA-sequencing data analyses reveal a comorbidity relationship between Alzheimer’s disease and lung cancer

2024-01-08

Abstract excerpt

<title>Abstract</title> <p>Numerous investigators have studied the correlation between Alzheimer’s disease (AD) and lung cancer (LC), yet a precise comprehension of their interconnection remains elusive. Prior studies have demonstrated the efficacy of certain targeted therapies for controlling ferroptosis in treating AD and LC. Moreover, ferroptosis plays a role in immune regulation. Therefore, this study aims to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6f5c0fe5-2df7-59f7-bf09-11e1f0e175e9
DOI: 10.21203/rs.3.rs-3831763/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Denoising autoencoder-based bulk and single-cell RNA-sequencing data analyses reveal a comorbidity relationship between Alzheimer’s disease and lung cancerDOI 10.21203/rs.3.rs-3831763/v1Read

A Bioinformatics Perspective on the Dysregulation of Ferroptosis and Ferroptosis-related Immune Cell Infiltration in Alzheimer's DiseaseSemantic proximity Read

Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s DiseaseSemantic proximity Read

Prediction of Alzheimer’s Disease from Single Cell Transcriptomics Using Deep LearningSemantic proximity Read

Neural Network-Enhanced Investigation of Ferroptosis and Druggability in Early-Onset Alzheimer’s DiseaseSemantic proximity Read

Analysis and experimental validation of necroptosis-related molecular classification, immune signature and feature genes in Alzheimer’s diseaseSemantic proximity Read

Using blood transcriptome analysis for Alzheimer's disease diagnosis and patient stratificationSemantic proximity Read

Bioinformatics analysis and prediction of Alzheimer’s disease and alcohol dependence based on Ferroptosis-related genesSemantic proximity Read

Molecular mechanism decipher of Alzheimer’s disease based on single-cell RNA-seq informationSemantic proximity Read

A meta-analysis of bulk RNA-seq datasets identifies potential biomarkers and repurposable therapeutics against Alzheimer’s diseaseSemantic proximity Read

Machine learning identification and immune infiltration of disulfidptosis‐related Alzheimer's disease molecular subtypesSemantic proximity Read

Identification ferroptosis-related hub genes and diagnostic model in Alzheimer’s diseaseSemantic proximity Read

Identification of Ferroptosis-Related Genes in Alzheimer’s Disease Based on Bioinformatic AnalysisSemantic proximity Read