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Analysis and experimental validation of necroptosis-related molecular classification, immune signature and feature genes in Alzheimer’s disease

13 Mar 2024

Abstract excerpt

Necroptosis, a programmed cell death pathway, has been demonstrated to be activated in Alzheimer's disease (AD). However, the precise role of necroptosis and its correlation with immune cell infiltration in AD remains unclear. In this study, we conducted non-negative matrix factorization clustering analysis to identify three subtypes of AD based on necroptosis-relevant genes. Notably, these subtypes exhibited...

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PMID: 38478169
DOI: 10.1007/s10495-024-01943-8

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