Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phagosomal Neutralization by the Fungal Pathogen Candida albicans Induces Macrophage Pyroptosis.

Infection and immunity - 1 Feb 2017

Vylkova Slavena, Lorenz Michael C

Abstract excerpt

The interaction of Candida albicans with the innate immune system is the key determinant of the pathogen/commensal balance and has selected for adaptations that facilitate the utilization of nutrients commonly found within the host, including proteins and amino acids; many of the catabolic pathways needed to assimilate these compounds are required for persistence in the host. We have shown that C. albicans...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Candida albicans
Share to Candidiasis
Share to Caspase 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Host-Pathogen Interactions

Share to Hyphae

Share to Immunity, Innate

Share to Interleukin-1beta

Share to Phagosomes

Source

Open in PubMed Open full text

Identifiers

PMID: 27872238
DOI: 10.1128/IAI.00832-16
PMCID: PMC5278172

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phagosomal Neutralization by the Fungal Pathogen Candida albicans Induces Macrophage Pyroptosis.PMID 27872238Read ↗

Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids.Semantic proximity Read ↗

The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH.Semantic proximity Read ↗

Role of Amino Acid Metabolism in the Virulence of Human Pathogenic FungiSemantic proximity Read ↗

Coordinated regulation of pH alkalinization by two transcription factors promotes fungal commensalism and pathogenicitySemantic proximity Read ↗

<i>Candida albicans</i> cells lacking AP-2 have defective hyphae and are avirulent despite increased host uptake and intracellular proliferation in macrophagesSemantic proximity Read ↗

Amino Acid Sensing and Assimilation by the Fungal Pathogen Candida albicans in the Human HostSemantic proximity Read ↗

Fungal hyphae instigate non-canonical inflammatory cell death in macrophagesSemantic proximity Read ↗

Respiration supports intraphagosomal filamentation and escape of Candida albicans from macrophagesSemantic proximity Read ↗

Candida auris —macrophage cellular interactions and transcriptional responseSemantic proximity Read ↗

Nutrient and Stress Sensing in Pathogenic YeastsSemantic proximity Read ↗

Candida albicans Csy1p is a nutrient sensor important for activation of amino acid uptake and hyphal morphogenesis.Semantic proximity Read ↗

Mitochondrial proline catabolism activates Ras1/cAMP/PKA-induced filamentation in <i>Candida albicans</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.